What is PGD?
PGD comes as a technique wherein the genetics of the embryos are analyzed and evaluated in order to find any possible issues before the embryo transfer process. The process is generally been brought in use when there is any kind of genetic abnormality in either of the partners who are going for the IVF treatment.
The PGD process is all about the genetic screening of the embryos before getting them transferred into the woman’s uterus and it also involves screening of the embryos for any kind of chromosomal abnormalities This process generally initiates with the IVF treatment where in the couples doesn’t want to transport any kind of genetic issues to their future child. It also comes beneficial in cases where the families of either of the partners are carrying along any kind of particular disease which is feared to be transmitted to the future child during the pregnancy period.
This Diagnosis also comes as best to check an embryo in terms of its genetics and further eliminates any such risk or issues attached to the related embryo during the IVF cycle. PGD always comes as a perfect genetic evaluation of an embryo which also confirms the total collection of chromosomes along with their count within the embryo. This is where the physician can track and diagnose any type of defect or issues attached to the embryo developed and fertilized during the IVF treatment which further enable them to take the required measures accordingly.
PGD may be recommended if:
- One or both the partners are coming with any kind of genetic disorder
- One or both the partners have a child already in their life coming along with any genetic abnormality
- The women under the observation has gone through several pregnancy terminations because of various genetic issues with the born child
Process of PGD
Ovarian Stimulation, Egg aspiration & In Vitro Fertilization:
The ovaries are stimulated here with all the proper medications in order to generate maximum number of eggs which are planned for fertilization process in the laboratory in order to produce bets quality and quantity of embryos.
The embryos are developed and fertilized until the 8 cell stage in the incubator during this process. During this process, one or two cells (blastomere) are eliminated by professionally trained embryologist to perform diagnosis. Moreover, it can also be obtained from 5-6 days blastocyst stage which comes along with more cells (>100) for better evaluation.
During this process, the cells are evaluated and tested to monitor the presence/absence of any kind of abnormality within the available embryos. Moreover, the embryos which are deemed free from any abnormal issues or defects are used for the embryo transfer process or been preserved with the cryopreservation process.